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Article

Characterizing Clinical and Neuropathological Traits of APOE Haplotypes in African Americans and Europeans.

Journal of Alzheimer's disease : JAD - 1 Jan 2020

Mezlini Aziz M, Magdamo Colin, Merrill Emily, Chibnik Lori B, Blacker Deborah L, Hyman Bradley T, Das Sudeshna

Abstract excerpt

BACKGROUND: The APOEɛ4 allele is the largest genetic risk factor for late-onset Alzheimer's disease (AD). Recent literature suggested that the contribution of APOEɛ4 to AD risk could be population-specific, with ɛ4 conferring a lower risk to Blacks or African Americans. OBJECTIVE: To investigate the effect of APOE haplotypes on AD risk in individuals with European ancestry (EU) and Blacks or African Americans...

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Identifiers

PMID: 33016904
DOI: 10.3233/JAD-200228
PMCID: PMC7774865

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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