Antisense RNA inhibition of phosphoprotein p18 expression abrogates the transformed phenotype of leukemic cells.

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Article

Antisense RNA inhibition of phosphoprotein p18 expression abrogates the transformed phenotype of leukemic cells.

Cancer research - 15 Mar 1996

Jeha S, Luo X N, Beran M, Kantarjian H, Atweh G F

Abstract excerpt

Phosphoprotein p18 was identified originally on the basis of its very high level of expression in leukemic cells of different lineages. Changes in the level of p18 accumulation and phosphorylation associated with induction of differentiation of leukemic cells suggested a potential role for this p...

Topics

Animals
Antimetabolites, Antineoplastic
Blotting, Southern
Cell Count
Cell Division
Cell Line, Transformed
Colony-Forming Units Assay
Culture Media
Female
Leukemia, Erythroblastic, Acute
Methotrexate
Mice
Mice, SCID
Microtubule Proteins
Phenotype
Phosphoproteins
RNA, Antisense
Stathmin

Source

Open in PubMed

Identifiers

PMID: 8640838

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8640838-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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