Article
Phosphorylation of human keratin 18 serine 33 regulates binding to 14-3-3 proteins.
The EMBO journal - 1 Apr 1998
Ku N O, Liao J, Omary M B
Abstract excerpt
Members of the 14-3-3 protein family bind the human intermediate filament protein keratin 18 (K18) in vivo, in a cell-cycle- and phosphorylation-dependent manner. We identified K18 Ser33 as an interphase phosphorylation site, which increases its phosphorylation during mitosis in cultured cells and regenerating liver, and as an in vitro cdc2 kinase phosphorylation site. Comparison of wild-type versus K18...
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