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Article

Antisense CD11b integrin inhibits the development of a differentiated monocyte/macrophage phenotype in human leukemia cells.

European journal of cell biology - 1 Jan 2002

Prudovsky Igor, Popov Konstantin, Akimov Sergey, Serov Sergey, Zelenin Alexander, Meinhardt Gerold, Baier Peter, Sohn Christoph, Hass Ralf

Abstract excerpt

Macrophage-like development of myeloid leukemia cells which can be induced by agents such as phorbol esters (TPA) is accompanied by integrin expression and cell adhesion. Thus, in differentiating myeloid leukemia cells CD11b is predominantly expressed which can associate with CD18 to form the functional heterodimeric integrin Mac-1. To elucidate the role of cell adhesion during macrophage-like differentiation, we...

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Identifiers

PMID: 11893077
DOI: 10.1078/0171-9335-00219

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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