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Article

Linkage studies with 17q and 18q markers in a breast/ovarian cancer family.

American journal of human genetics - 1 Apr 1993

Milner B J, Allan L A, Kelly K F, Cruickshank D, Hall M, Johnston A, Kitchener H, Parkin D, Haites N

Abstract excerpt

Genes on chromosomes 17q and 18q have been shown to code for putative tumor suppressors. By a combination of allele-loss studies on sporadic ovarian carcinomas and linkage analysis on a breast/ovarian cancer family, we have investigated the involvement of such genes in these diseases. Allele loss occurred in sporadic tumors from both chromosome 17p, in 18/26 (69%) cases, and chromosome 17q, in 15/22 (68%) cases....

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PMID: 8096360
PMCID: PMC1682079

Genes

DCC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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