Linkage studies with 17q and 18q markers in a breast/ovarian cancer family.

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Article

Linkage studies with 17q and 18q markers in a breast/ovarian cancer family.

American journal of human genetics - 1 Apr 1993

Milner B J, Allan L A, Kelly K F, Cruickshank D, Hall M, Johnston A, Kitchener H, Parkin D, Haites N

Abstract excerpt

Genes on chromosomes 17q and 18q have been shown to code for putative tumor suppressors. By a combination of allele-loss studies on sporadic ovarian carcinomas and linkage analysis on a breast/ovarian cancer family, we have investigated the involvement of such genes in these diseases. Allele loss...

Topics

Adult
Aged
Alleles
Blotting, Southern
Breast Neoplasms
Chromosome Deletion
Chromosome Mapping
Chromosomes, Human, Pair 17
Chromosomes, Human, Pair 18
DNA, Neoplasm
Family Health
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, DCC

Genes, Tumor Suppressor

Genetic Linkage

Genetic Markers

Genetic Predisposition to Disease

Humans

Source

Open in PubMed Open full text

Identifiers

PMID: 8096360
PMCID: PMC1682079

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8096360-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Linkage studies with 17q and 18q markers in a breast/ovarian cancer family.PMID 8096360Read ↗

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CGH analysis of familial non-BRCA1/BRCA2 breast tumors and mutation screening of a candidate locus on chromosome 17q11.2-12.Semantic proximity Read ↗

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