The p53 gene in pediatric therapy-related leukemia and myelodysplasia.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

The p53 gene in pediatric therapy-related leukemia and myelodysplasia.

Blood - 15 May 1996

Felix C A, Hosler M R, Provisor D, Salhany K, Sexsmith E A, Slater D J, Cheung N K, Winick N J, Strauss E A, Heyn R, Lange B J, Malkin D

Abstract excerpt

We investigated the frequency of p53 mutations in 19 pediatric cases of therapy-related leukemia or myelodysplastic syndrome. Eleven children presented with acute myeloid leukemia, one with mixed-lineage leukemia, two with acute lymphoblastic leukemia, and five with myelodysplasia at times rangin...

Topics

Adolescent
Antimetabolites, Antineoplastic
Antineoplastic Agents, Alkylating
Base Sequence
Bone Marrow
Child
Child, Preschool
Codon
Combined Modality Therapy
DNA, Neoplasm
Female
Genes, p53
Genetic Predisposition to Disease
Humans
Infant

Source

Open in PubMed

Identifiers

PMID: 8639798

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8639798-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Leukemia

Leukemia, Radiation-Induced

Li-Fraumeni Syndrome