Article
Fetal RhD genotyping in fetal cells flow sorted from maternal blood.
American journal of obstetrics and gynecology - 1 Mar 1996
Geifman-Holtzman O, Bernstein I M, Berry S M, Holtzman E J, Vadnais T J, DeMaria M A, Bianchi D W
Abstract excerpt
OBJECTIVE: The aim of this study was to determine the accuracy of noninvasive fetal RhD genotyping by fetal cell isolation from maternal blood. STUDY DESIGN: Candidate fetal cells from 18 pregnant women (one twin gestation) were flow-sorted. Polymerase chain reaction amplification of a 261 bp fragment of the RhD gene was performed on sorted fetal cells. The presence of amplified product was considered predictive...
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