Article
Evaluation of prenatal RHD typing strategies on cell-free fetal DNA from maternal plasma.
Transfusion - 1 Dec 2006
Grootkerk-Tax Martine G H M, Soussan Aicha Ait, de Haas Masja, Maaskant-van Wijk Petra A, van der Schoot C Ellen
Abstract excerpt
BACKGROUND: The discovery of cell-free fetal DNA in maternal plasma led to the development of assays to predict the fetal D status with RHD-specific sequences. Few assays are designed in such a way that the fetus can be typed in RHDpsi mothers and that RHDpsi fetuses are correctly typed. Owing to the limited knowledge about the mechanism responsible for the presence of fetal DNA in maternal plasma, precautions in...
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