Article
Multiplexed analysis of circulating cell-free fetal nucleic acids for noninvasive prenatal diagnostic RHD testing.
American journal of obstetrics and gynecology - 1 Mar 2011
Tynan John A, Angkachatchai Vach, Ehrich Mathias, Paladino Toni, van den Boom Dirk, Oeth Paul
Abstract excerpt
OBJECTIVE: The objective of the study was the evaluation of a novel multiplex assay to detect fetal Rh blood group D-antigen gene (RHD) loci in maternal plasma from RhD-negative, pregnant women. STUDY DESIGN: An RHD genotyping assay was designed to detect exons 4, 5, 7, and 10 and RHDΨ (pseudogene) of the RHD gene along with a Y chromosome-specific assay and a generic polymerase chain reaction amplification...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
