Article
The head involution defective gene of Drosophila melanogaster functions in programmed cell death.
Genes & development - 15 Jul 1995
Grether M E, Abrams J M, Agapite J, White K, Steller H
Abstract excerpt
Deletions of chromosomal region, 75C1,2 block virtually all programmed cell death (PCD) in the Drosophila embryo. We have identified a gene previously in this interval, reaper (rpr), which encodes an important regulator of PCD. Here we report the isolation of a second gene in this region, head in...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Apoptosis
- Base Sequence
- Chromosome Mapping
- Cloning, Molecular
- DNA
- DNA Primers
- Drosophila Proteins
- Drosophila melanogaster
- Eye Abnormalities
- Gene Deletion
- Genes, Insect
- Models, Genetic
- Molecular Sequence Data
- Neuropeptides
- RNA, Messenger