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Article

Recognition of altered self major histocompatibility complex molecules modulated by specific peptide interactions.

European journal of immunology - 1 Apr 1996

Nepom G T, Ou D, Lybrand T P, DeWeese C, Domeier M E, Buckner J H, Mitchell L A, Tingle A J

Abstract excerpt

Antigen-specific and major histocompatibility complex (MHC)-restricted recognition by the T cell receptor involves multiple structural contacts over a large molecular surface area. Using a human T cell clone specific for a rubella viral peptide restricted by subsets of HLA DR4 molecules, we identified structurally diverse combinations of peptide-MHC complexes which were functionally equivalent to T cell...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8625994
DOI: 10.1002/eji.1830260435

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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