Recognition of contiguous allele-specific peptide elements in the rubella virus E1 envelope protein.

doi:10.1016/s0264-410x(96)00194-6

Back to search

Article

Recognition of contiguous allele-specific peptide elements in the rubella virus E1 envelope protein.

Vaccine - 1 Jan 2000

Nepom G T, Domeier M E, Ou D, Kovats S, Mitchell L A, Tingle A J

Abstract excerpt

Peptides which bind to human HLA-DRB1 class II molecules in an allele-specific fashion were derived from the immunodominant E1 envelope protein of rubella virus. Two nonoverlapping E1 peptide epitopes were recognized by rubella virus-specific T cells in the context of independent HLA alleles when...

Topics

Alleles
CD4-Positive T-Lymphocytes
Cell Line, Transformed
Epitope Mapping
Epitopes, T-Lymphocyte
HLA-DR Antigens
HLA-DRB1 Chains
Humans
Immunodominant Epitopes
Peptides
Rubella virus
Viral Envelope Proteins

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.