Article
Recognition of contiguous allele-specific peptide elements in the rubella virus E1 envelope protein.
Vaccine - 1 Jan 2000
Nepom G T, Domeier M E, Ou D, Kovats S, Mitchell L A, Tingle A J
Abstract excerpt
Peptides which bind to human HLA-DRB1 class II molecules in an allele-specific fashion were derived from the immunodominant E1 envelope protein of rubella virus. Two nonoverlapping E1 peptide epitopes were recognized by rubella virus-specific T cells in the context of independent HLA alleles when presented either separately or as a contiguous polypeptide containing both epitopes. Direct binding analysis of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
