Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A genomic polymorphism within the tumor necrosis factor locus influences plasma tumor necrosis factor-alpha concentrations and outcome of patients with severe sepsis.

Critical care medicine - 1 Mar 1996

Stüber F, Petersen M, Bokelmann F, Schade U

Abstract excerpt

OBJECTIVES: To determine the allele frequency and genotype distribution of a bi-allelic tumor necrosis factor (TNF) gene polymorphism and plasma TNF-alpha concentrations in postoperative intensive care unit (ICU) patients suffering from severe sepsis. DESIGN: Prospective, consecutive entry study...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Disease
Share to Alleles
Share to TNF gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Human

Share to Genotype

Share to Molecular Sequence Data

Share to Polymorphism, Genetic

Share to Sepsis

Source

Identifiers

PMID: 8625623
DOI: 10.1097/00003246-199603000-00004

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-8625623-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A genomic polymorphism within the tumor necrosis factor locus influences plasma tumor necrosis factor-alpha concentrations and outcome of patients with severe sepsis.PMID 8625623Read ↗

Tumor necrosis factor gene polymorphisms, leukocyte function, and sepsis susceptibility in blunt trauma patients.Semantic proximity Read ↗

Tumor necrosis factor-β Nco1 polymorphism and susceptibility to sepsis following major elective surgery.Semantic proximity Read ↗

Influence of the TNF-alpha and TNF-beta polymorphisms upon infectious risk and outcome in surgical intensive care patients.Semantic proximity Read ↗

Relation of a TNF gene polymorphism to severe sepsis in trauma patients.Semantic proximity Read ↗

Are postoperative complications genetically determined by TNF-beta NcoI gene polymorphism?Semantic proximity Read ↗

Tumor necrosis factor gene polymorphism is associated with enhanced systemic inflammatory response and increased cardiopulmonary morbidity after cardiac surgery.Semantic proximity Read ↗

Comparison of two polymorphisms of the interleukin-1 gene family: interleukin-1 receptor antagonist polymorphism contributes to susceptibility to severe sepsis.Semantic proximity Read ↗

Association of TNF2, a TNF-alpha promoter polymorphism, with septic shock susceptibility and mortality: a multicenter study.Semantic proximity Read ↗

Pilot study assessing TNF gene polymorphism as a prognostic marker for disease progression in neonates with sepsis.Semantic proximity Read ↗

Gender Differences in Sepsis: Genetically Determined?Semantic proximity Read ↗

GENDER DIFFERENCES IN SEPSIS: GENETICALLY DETERMINED?Semantic proximity Read ↗

Analysis of two human leukocyte antigen-linked polymorphic heat shock protein 70 genes in patients with severe sepsis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.