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Article

Relation of a TNF gene polymorphism to severe sepsis in trauma patients.

Annals of surgery - 1 Aug 1999

Majetschak M, Flohé S, Obertacke U, Schröder J, Staubach K, Nast-Kolb D, Schade F U, Stüber F

Abstract excerpt

OBJECTIVE: To investigate the relation of the biallelic Nco1 restriction fragment length polymorphism in the first intron of the tumor necrosis factor (TNF) beta gene with the development of severe sepsis in multiply injured patients. SUMMARY BACKGROUND DATA: The biallelic Nco1 polymorphism of the TNFbeta gene has been described to be associated with autoimmune diseases and with the mortality rate in severe...

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Source

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Identifiers

PMID: 10450735
DOI: 10.1097/00000658-199908000-00011
PMCID: PMC1420863

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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