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Article

Are postoperative complications genetically determined by TNF-beta NcoI gene polymorphism?

Surgery - 1 Apr 2004

Kahlke Volker, Schafmayer Clemens, Schniewind Bodo, Seegert Dirk, Schreiber Stefan, Schröder Jörg

Abstract excerpt

BACKGROUND: Postoperative infectious complications are the leading causes for postoperative sepsis. In severe sepsis, tumor necrosis factor-beta (TNF-beta) NcoI polymorphism was associated with increased mortality. Therefore, the aim of this study was to determine whether the biallelic NcoI polymorphism within the TNF locus is associated with the development of postoperative complications. METHODS: One hundred...

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Source

Identifiers

PMID: 15041959
DOI: 10.1016/j.surg.2003.08.012

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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