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Article

Pilot study assessing TNF gene polymorphism as a prognostic marker for disease progression in neonates with sepsis.

Infection - 1 Jan 2000

Weitkamp J H, Stüber F, Bartmann P

Abstract excerpt

In adult postoperative intensive care patients, the biallelic Ncol polymorphism within the tumor necrosis factor (TNF) locus has been shown to be a genomic marker for individuals with increased TNF-alpha response and poor prognosis in severe sepsis. We characterized the genomic distribution and allele frequency of the Ncol polymorphism in 23 preterm and term neonatal intensive care unit (NICU) patients with...

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Source

Identifiers

PMID: 10782394
DOI: 10.1007/s150100050053

Genes

TNF
CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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