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Article

Tumor necrosis factor gene polymorphisms, leukocyte function, and sepsis susceptibility in blunt trauma patients.

Clinical and diagnostic laboratory immunology - 1 Nov 2002

Majetschak Matthias, Obertacke Udo, Schade F Ulrich, Bardenheuer Mark, Voggenreiter Gregor, Bloemeke Brunhilde, Heesen Michael

Abstract excerpt

The tumor necrosis factor alpha (TNF-alpha) -308 G/A and TNF-beta NcO1 polymorphisms have been described to be associated with an increased risk for sepsis in critically ill patients. Functional consequences associated with these polymorphisms remain unclear. We compared the genotype distribution of these TNF polymorphisms with susceptibility to severe sepsis and leukocyte function in blunt trauma patients (n =...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 12414751
DOI: 10.1128/cdli.9.6.1205-1211.2002
PMCID: PMC130126

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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