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Article

Tumor necrosis factor-β Nco1 polymorphism and susceptibility to sepsis following major elective surgery.

Surgical infections - 1 Jun 2014

Baghel Kavita, Srivastava Rajeshwar Nath, Chandra Abhijit, Raj Saloni, Goel Sudhir K, Pant Aditya Bhusan, Agrawal Jyotsna

Abstract excerpt

BACKGROUND: Post-operative sepsis remains a substantial cause of morbidity and mortality. In injured patients, that a polymorphism of the gene for tumor necrosis factor-β (TNF-β) has been related to the development of sepsis. Genetic factors may also have a role in etio-pathogenesis of sepsis following surgery. We investigated the relationship of the polymorphism of the gene for TNF-β and the serum concentration...

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Source

Identifiers

PMID: 24796628
DOI: 10.1089/sur.2012.211

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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