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Article

Gender Differences in Sepsis: Genetically Determined?

1 May 2000

Abstract excerpt

In the pathogenesis of sepsis, tumor necrosis factor (TNF) release and host reaction may be genetically determined as demonstrated for TNFbeta Ncol polymorphism. Gender differences are considered as another important prognostic variable in patients with sepsis with better survival for women. The effect of sexual dimorphism on the genetic background of sepsis, however, is unknown. In a prospective study at two...

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PMID: 11028548
DOI: 10.1097/00024382-200005000-00046

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