Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparison of two polymorphisms of the interleukin-1 gene family: interleukin-1 receptor antagonist polymorphism contributes to susceptibility to severe sepsis.

Critical care medicine - 1 Jul 1999

Fang X M, Schröder S, Hoeft A, Stüber F

Abstract excerpt

OBJECTIVES: To determine whether the allele frequencies and genotype distribution of an interleukin (IL)-1beta TaqI polymorphism and an interleukin-1 receptor antagonist polymorphism are associated with susceptibility to and outcome of severe sepsis. In addition, we analyze a possible linkage disequilibrium between a previously described NcoI polymorphism within the tumor necrosis factor (TNF) locus and the two...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Germany
Share to Interleukin-1
Share to Odds Ratio

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Receptors, Interleukin-1

Share to Sepsis

Share to Statistics, Nonparametric

Share to Survival Rate

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 10446828
DOI: 10.1097/00003246-199907000-00024

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparison of two polymorphisms of the interleukin-1 gene family: interleukin-1 receptor antagonist polymorphism contributes to susceptibility to severe sepsis.PMID 10446828Read ↗

Genomic polymorphism within interleukin-1 family cytokines influences the outcome of septic patients.Semantic proximity Read ↗

[Genomic polymorphism within interleukin-1 family cytokines influences the outcome of septic patients].Semantic proximity Read ↗

Interleukin-1 receptor antagonist gene polymorphism and mortality in patients with severe sepsis.Semantic proximity Read ↗

A genomic polymorphism within the tumor necrosis factor locus influences plasma tumor necrosis factor-alpha concentrations and outcome of patients with severe sepsis.Semantic proximity Read ↗

TNF -308G > a promoter polymorphism (rs1800629) and outcome from critical illness.Semantic proximity Read ↗

Associations between interleukin-1 gene polymorphisms and sepsis risk: a meta-analysis.Semantic proximity Read ↗

TNF and TNFR polymorphisms in severe sepsis and septic shock: a prospective multicentre study.Semantic proximity Read ↗

Tumor necrosis factor gene polymorphisms, leukocyte function, and sepsis susceptibility in blunt trauma patients.Semantic proximity Read ↗

The TNF-α (-238 G/A) polymorphism could protect against development of severe sepsis.Semantic proximity Read ↗

Influence of the TNF-alpha and TNF-beta polymorphisms upon infectious risk and outcome in surgical intensive care patients.Semantic proximity Read ↗

[Association of different alleles in interleukin-1 family genes with the coded cytokines production and outcome of sepsis].Semantic proximity Read ↗

Tumor necrosis factor-β Nco1 polymorphism and susceptibility to sepsis following major elective surgery.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.