Evidence for a unifocal origin in familial ovarian cancer.

doi:10.1016/s0002-9378(96)70651-8

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Article

Evidence for a unifocal origin in familial ovarian cancer.

American journal of obstetrics and gynecology - 1 Apr 1996

Gallion H H, Guarino A, DePriest P D, van Nagell J R, Vaccarello L, Berek J S, Pieretti M

Abstract excerpt

OBJECTIVE: The purpose of this investigation was to determine the pattern of loss of heterozygosity in multiple tumor sites from familial ovarian cancer cases. If ovarian cancer arises focally in one ovary and then metastasizes to other sites, a similar pattern should be seen in all tumor sites....

Topics

Alleles
Chromosomes, Human, Pair 1
Chromosomes, Human, Pair 11
Chromosomes, Human, Pair 13
Chromosomes, Human, Pair 16
Chromosomes, Human, Pair 17
Chromosomes, Human, Pair 6
Female
Heterozygote
Humans
Neoplasm Metastasis
Ovarian Neoplasms

Source

Open in PubMed

Identifiers

PMID: 8623836
DOI: 10.1016/s0002-9378(96)70651-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8623836-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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