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Article

Evidence for a unifocal origin in familial ovarian cancer.

American journal of obstetrics and gynecology - 1 Apr 1996

Gallion H H, Guarino A, DePriest P D, van Nagell J R, Vaccarello L, Berek J S, Pieretti M

Abstract excerpt

OBJECTIVE: The purpose of this investigation was to determine the pattern of loss of heterozygosity in multiple tumor sites from familial ovarian cancer cases. If ovarian cancer arises focally in one ovary and then metastasizes to other sites, a similar pattern should be seen in all tumor sites. However, if ovarian cancer arises multifocally throughout the peritoneal cavity, a different pattern of loss would be...

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Identifiers

PMID: 8623836
DOI: 10.1016/s0002-9378(96)70651-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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