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Article

Molecular genetic evidence of a unifocal origin for human serous ovarian carcinomas.

Gynecologic oncology - 1 Jan 1993

Tsao S W, Mok C H, Knapp R C, Oike K, Muto M G, Welch W R, Goodman H M, Sheets E E, Berkowitz R S, Lau C C

Abstract excerpt

The hypothesis that ovarian cancer is multifocal in origin was examined using molecular genetic techniques. Patterns of allelic deletion on chromosome 17 were studied in 16 informative cases of Stage III serous epithelial ovarian carcinoma. DNA was extracted from specimens collected from the omentum and both ovaries, and the specific alleles and chromosomal loci involved in the deletion were identified and...

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Share to Blotting, Southern
Share to Chromosomes, Human, Pair 17

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neoplasms, Multiple Primary

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Source

Identifiers

PMID: 8423021
DOI: 10.1006/gyno.1993.1002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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