Article
Different pattern of chromosomal allele loss in multiple hepatocellular carcinomas as evidence of their multifocal origin.
Cancer research - 15 Mar 1992
Tsuda H, Oda T, Sakamoto M, Hirohashi S
Abstract excerpt
One of the most problematic aspects of surgery for hepatocellular carcinoma (HCC) is the frequent development of multiple tumors. Determination of the origin of multiple tumors, i.e., multifocal or metastatic, is important for predicting the clinical course of the disease after surgery. In order...
Topics
- Alleles
- Carcinoma, Hepatocellular
- Chromosome Deletion
- Chromosomes, Human, Pair 16
- Heterozygote
- Humans
- Liver Neoplasms
- Neoplasms, Multiple Primary
- Polymorphism, Restriction Fragment Length