Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Possible involvement of loss of heterozygosity in malignant transformation of ovarian endometriosis.

Gynecologic oncology - 1 Feb 2011

Xu Bing, Hamada Shinshichi, Kusuki Izumi, Itoh Ryoji, Kitawaki Jo

Abstract excerpt

OBJECTIVE: Although histological and epidemiological studies have suggested that endometriosis has malignant potential, the molecular mechanism underlying the malignant transformation of endometriosis is poorly understood. Ovarian cancer arising from endometriosis (OCEM) may provide an ideal model for genetic studies. To investigate the genetic alterations during transformation of ovarian endometriosis into...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma, Clear Cell
Share to Carcinoma, Endometrioid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endometriosis

Share to Genes, ras

Share to Genes, Tumor Suppressor

Share to Loss of Heterozygosity

Share to Paraffin Embedding

Share to PTEN Phosphohydrolase

Source

Identifiers

PMID: 21130491
DOI: 10.1016/j.ygyno.2010.10.036

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Possible involvement of loss of heterozygosity in malignant transformation of ovarian endometriosis.PMID 21130491Read ↗

Possible relevance of tumor-related genes mutation to malignant transformation of endometriosis.Semantic proximity Read ↗

Molecular genetic evidence that endometriosis is a precursor of ovarian cancerSemantic proximity Read ↗

Genomic alterations in ovarian endometriosis and subsequently diagnosed ovarian carcinoma.Semantic proximity Read ↗

Patterns of loss of heterozygosity at 10q23.3 and microsatellite instability in endometriosis, atypical endometriosis, and ovarian carcinoma arising in association with endometriosis.Semantic proximity Read ↗

Ovarian endometriosis, a precursor of ovarian cancer: Histological aspects, gene expression and microRNA alterations (Review)Semantic proximity Read ↗

Endometriosis and endometriosis-associated cancers: new insights into the molecular mechanisms of ovarian cancer developmentSemantic proximity Read ↗

Microsatellite analysis of endometriosis reveals loss of heterozygosity at candidate ovarian tumor suppressor gene loci.Semantic proximity Read ↗

Endometriosis-associated Ovarian Cancers.Semantic proximity Read ↗

Endometriosis-Associated Ovarian Cancer: The Origin and Targeted TherapySemantic proximity Read ↗

Comprehensive allelotype study of ovarian tumors of low malignant potential: potential differences in pathways between tumors with and without genetic predisposition to invasive carcinoma.Semantic proximity Read ↗

Common genetic changes between endometriosis and ovarian cancer.Semantic proximity Read ↗

The relationship of endometriosis and ovarian malignancy: a review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.