Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Glycophorin A mutations and risk of secondary leukaemia in patients treated for childhood acute lymphoblastic leukaemia.

British journal of haematology - 1 Apr 1996

Boyse J, Hewitt M, Mott M G

Abstract excerpt

Survivors of child acute lymphoblastic leukaemia (ALL) have a higher than expected risk of developing secondary acute myeloid leukaemia (AML). The glycophorin A (GPA) mutation assay measures the frequency of variant NO and NN erythrocytes in MN heterozygotes. A raised variant frequency (Vf) has been shown in patients treated with chemotherapy known to be at risk of secondary leukaemia. ALL patients were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Disease
Share to Child
Share to Child, Preschool

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Markers

Share to Genetic Techniques

Share to Mutation

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Source

Identifiers

PMID: 8611443
DOI: 10.1046/j.1365-2141.1996.4621001.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Glycophorin A mutations and risk of secondary leukaemia in patients treated for childhood acute lymphoblastic leukaemia.PMID 8611443Read ↗

Do mutations at the glycophorin A locus in patients treated for childhood Hodgkin's disease predict secondary leukaemia?Semantic proximity Read ↗

The GPA in vivo somatic mutation assay.Semantic proximity Read ↗

The assessment of in vivo somatic mutations in survivors of childhood malignancy.Semantic proximity Read ↗

In vivo somatic mutation and segregation at the human glycophorin A (GPA) locus: phenotypic variation encompassing both gene-specific and chromosomal mechanisms.Semantic proximity Read ↗

The blood-based glycophorin A (GPA) human in vivo somatic mutation assay.Semantic proximity Read ↗

Increased frequency of somatic mutations at glycophorin A loci in patients with aplastic anaemia, myelodysplastic syndrome and paroxysmal nocturnal haemoglobinuria.Semantic proximity Read ↗

Neonatal vitamin K administration and in vivo somatic mutation.Semantic proximity Read ↗

Elevated somatic mutation and evidence of genomic instability in veterans with Gulf War illness.Semantic proximity Read ↗

Frequencies of HPRT- lymphocytes and glycophorin A variants erythrocytes in Fanconi anemia patients, their parents and control donors.Semantic proximity Read ↗

Increased glycophorin A somatic cell variant frequency in arsenic-exposed patients of Guizhou, China.Semantic proximity Read ↗

Analysis of erythrocyte glycophorin-A variants by flow cytometry in lung disease patients detects the effect of tobacco smoke.Semantic proximity Read ↗

Polymorphisms of the DNA repair gene XRCC1 and the frequency of somatic mutations at the glycophorin A locus in newborns.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.