Article
The assessment of in vivo somatic mutations in survivors of childhood malignancy.
British journal of cancer - 1 Jul 1992
Hewitt M, Mott M G
Abstract excerpt
The assessment of chromosomal mutations in children may provide information about aetiology and risk of second malignancies. A somatic cell mutation assay which determines variant erythrocytes lacking expression of an allelic form of the sialoglycoprotein, glycophorin A, was applied to samples from children before and after receiving potentially genotoxic therapy. Fifty-six children who had received treatment for...
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