Article
Do mutations at the glycophorin A locus in patients treated for childhood Hodgkin's disease predict secondary leukaemia?
Lancet (London, England) - 2 Apr 1994
Mott M G, Boyse J, Hewitt M, Radford M
Abstract excerpt
Childhood Hodgkin's disease has a high cure rate but second cancers are common, related to treatment and perhaps genetic predisposition. The glycophorin A (GPA) mutation assay measures the frequency of NO and NN mutant erythrocytes of MN blood-group heterozygous individuals. Mutant frequencies in Hodgkin's disease patients were compared with controls. No significant difference from controls was found pretreatment...
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