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Article

Neonatal vitamin K administration and in vivo somatic mutation.

Mutation research - 1 Aug 1995

Pizer B, Boyse J, Hunt L, Mott M

Abstract excerpt

The glycophorin A (GPA) mutation assay was used to examine the risk of in vivo somatic mutation in infants following neonatal administration of vitamin K. The assay assesses damage to erythroid stem cells by measuring the frequency of NO and NN variant red cells of MN blood group heterozygotes using FACS analysis. Blood samples were obtained from 178 infants aged between 10 and 183 days. Twenty-six children were...

Topics

Administration, Oral
Erythrocytes
Flow Cytometry
Follow-Up Studies
Genetic Variation
Glycophorins
Hematopoietic Stem Cells
Heterozygote
Humans
Infant
Infant, Newborn
Injections, Intramuscular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Injections, Intravenous

Mutagenesis

Mutagenicity Tests

Phenotype

Vitamin K

Source

Identifiers

PMID: 7565904
DOI: 10.1016/0165-7992(95)00032-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7565904-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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