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Article

Abnormal complement-mediated immune clearance in MRL-lpr/+ heterozygote mice: dose-dependent effect of the Fas antigen mutation.

Clinical immunology and immunopathology - 1 Mar 1996

Meryhew N L, Tam P E, Seim J K, Messner R P

Abstract excerpt

We have previously demonstrated decreased complement-mediated clearance of IgG-opsonized erythrocytes in mice homozygous for the lpr mutation of the fas gene (BALB/c-lpr/lpr, C57BL/6-lpr/lpr, and MRL-lpr/lpr). To further test the hypothesis that the lpr mutation leads to a series of events resulting in selectively decreased complement-mediated immune clearance, in vivo clearance rate data were obtained from...

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Identifiers

PMID: 8605699
DOI: 10.1006/clin.1996.0035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Abnormal complement-mediated immune clearance in MRL-lpr/+ heterozygote mice: dose-dependent effect of the Fas antigen mutation.PMID 8605699Read ↗

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