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Article

Molecular analysis of HLA-DQB1 alleles in childhood common acute lymphoblastic leukaemia.

British journal of cancer - 1 Mar 1996

Dearden S P, Taylor G M, Gokhale D A, Robinson M D, Thompson W, Ollier W, Binchy A, Birch J M, Stevens R F, Carr T, Bardsley W G

Abstract excerpt

Epidemiological studies suggest that childhood common acute lymphoblastic leukaemia (c-ALL) may be the rare outcome of early post-natal infection with a common infectious agent. One of the factors that may determine whether a child succumbs to c-ALL is how it responds to the candidate infection. Since immune responses to infection are under the partial control of (human leucocyte antigen) HLA genes, an...

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Identifiers

PMID: 8605093
DOI: 10.1038/bjc.1996.104
PMCID: PMC2074350

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Molecular analysis of HLA-DQB1 alleles in childhood common acute lymphoblastic leukaemia.PMID 8605093Read ↗

Preliminary evidence of an association between HLA-DPB1*0201 and childhood common acute lymphoblastic leukaemia supports an infectious aetiology.Semantic proximity Read ↗

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Evidence that an HLA-DQA1-DQB1 haplotype influences susceptibility to childhood common acute lymphoblastic leukaemia in boys provides further support for an infection-related aetiology.Semantic proximity Read ↗

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