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Article

MHC variation and risk of childhood B-cell precursor acute lymphoblastic leukemia.

Blood - 3 Feb 2011

Hosking Fay J, Leslie Stephen, Dilthey Alexander, Moutsianas Loukas, Wang Yufei, Dobbins Sara E, Papaemmanuil Elli, Sheridan Eamonn, Kinsey Sally E, Lightfoot Tracy, Roman Eve, Irving Julie A E, Allan James M, Taylor Malcolm, Greaves Mel, McVean Gilean, Houlston Richard S

Abstract excerpt

A role for specific human leukocyte antigen (HLA) variants in the etiology of childhood acute lymphoblastic leukemia (ALL) has been extensively studied over the last 30 years, but no unambiguous association has been identified. To comprehensively study the relationship between genetic variation within the 4.5 Mb major histocompatibility complex genomic region and precursor B-cell (BCP) ALL risk, we analyzed 1075...

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PMID: 21059899
DOI: 10.1182/blood-2010-08-301598

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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