Article
Preliminary evidence of an association between HLA-DPB1*0201 and childhood common acute lymphoblastic leukaemia supports an infectious aetiology.
Leukemia - 1 Mar 1995
Taylor G M, Robinson M D, Binchy A, Birch J M, Stevens R F, Jones P M, Carr T, Dearden S, Gokhale D A
Abstract excerpt
It has been suggested that childhood leukaemia may be the abnormal outcome of a common infection. Rare events caused by common environmental events such as infections are likely to be influenced by host genetic susceptibility. We have therefore investigated whether immunogenetic susceptibility contributes to the risk of childhood common ALL (c-ALL). In this preliminary study, we report that children with c-ALL (n...
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