Article
Preliminary evidence of an association between HLA-DPB1*0201 and childhood common acute lymphoblastic leukaemia supports an infectious aetiology.
Leukemia - 1 Mar 1995
Taylor G M, Robinson M D, Binchy A, Birch J M, Stevens R F, Jones P M, Carr T, Dearden S, Gokhale D A
Abstract excerpt
It has been suggested that childhood leukaemia may be the abnormal outcome of a common infection. Rare events caused by common environmental events such as infections are likely to be influenced by host genetic susceptibility. We have therefore investigated whether immunogenetic susceptibility co...
Topics
- Adolescent
- Alleles
- Child
- Child, Preschool
- Disease Susceptibility
- Female
- Genetic Predisposition to Disease
- Genotype
- HLA-DP Antigens
- HLA-DP beta-Chains
- Humans
- Infant
- Infections
- Male
- Polymerase Chain Reaction
- Precursor B-Cell Lymphoblastic Leukemia-Lymphoma