Article
Lack of association between childhood common acute lymphoblastic leukaemia and an HLA-C locus dimorphism influencing the specificity of natural killer cells.
British journal of haematology - 1 Sept 1998
Ghodsi K, Taylor G M, Gokhale D A, Dearden S, Stevens R F, Birch J M, Fergusson W D, Eden O B, Ollier W
Abstract excerpt
Previous serological studies documenting an association between acute lymphoblastic leukaemia (ALL) and HLA-Cw antigens suggested that the HLA-C locus might influence susceptibility to ALL. However, associations with more than one Cw antigen suggest that polymorphic variants shared by more than C...
Topics
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- HLA-C Antigens
- Heterozygote
- Homozygote
- Humans
- Killer Cells, Natural
- Male
- Precursor Cell Lymphoblastic Leukemia-Lymphoma