Article
p53 abnormalities in splenic lymphoma with villous lymphocytes.
Blood - 1 Jun 2001
Gruszka-Westwood A M, Hamoudi R A, Matutes E, Tuset E, Catovsky D
Abstract excerpt
The incidence and role of p53 abnormalities have not been reported in splenic lymphoma with villous lymphocytes (SLVL), the leukemic counterpart of splenic marginal zone lymphoma. Because p53 abnormalities correlate with progressive and refractory disease in cancer and isochromosome 17q has been described in SLVL, a low-grade lymphoma that behaves aggressively in a minority of patients, this study investigated...
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