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Article

Genetic and molecular analysis of the autosomal component of the primary sex determination signal of Drosophila melanogaster.

Genetics - 1 Dec 1995

Barbash D A, Cline T W

Abstract excerpt

Drosophila sex is determined by the action of the X:A chromosome balance on transcription of Sex-lethal (Sxl), a feminizing switch gene. We obtained loss-of-function mutations in denominator elements of the X:A signal by selecting for dominant suppressors of a female-specific lethal mutation in the numerator element, sisterlessA (sisA). Ten suppressors were recovered in this extensive genome-wide selection. All...

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Identifiers

PMID: 8601486
DOI: 10.1093/genetics/141.4.1451
PMCID: PMC1206879

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Genetic and molecular analysis of the autosomal component of the primary sex determination signal of Drosophila melanogaster.PMID 8601486Read ↗

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