Article
The Drosophila melanogaster sex determination gene sisA is required in yolk nuclei for midgut formation.
Genetics - 1 May 2000
Walker J J, Lee K K, Desai R N, Erickson J W
Abstract excerpt
During sex determination, the sisterlessA (sisA) gene functions as one of four X:A numerator elements that set the alternative male or female regulatory states of the switch gene Sex-lethal. In somatic cells, sisA functions specifically in sex determination, but its expression pattern also hints at a role in the yolk cell, a syncytial structure believed to provide energy and nutrients to the developing embryo....
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Basic-Leucine Zipper Transcription Factors
- Cell Nucleus
- DNA-Binding Proteins
- Digestive System
- Drosophila Proteins
- Drosophila melanogaster
- Endoderm
- Female
- Genes, Insect
- Male
- Molecular Sequence Data
- Mutagenesis
- Phenotype
- Sex Determination Processes
- Temperature