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Article

A lesson from flex: consider the Y chromosome when assessing Drosophila sex-specific lethals.

Development (Cambridge, England) - 1 Mar 2001

Cline T W

Abstract excerpt

Bhattacharya et al. (Bhattacharya, A., Sudha, S., Chandra, H. S. and Steward, R. (1999) Development 126, 5485-5493) reported that loss-of-function mutations in the flex (female-specific lethal on X) gene caused female-specific lethality because flex(+) acts as a positive regulator of the master switch gene Sex lethal (Sxl). Sxl is essential for female development. Key to their conclusion was the ability of flex...

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Identifiers

PMID: 11222155
DOI: 10.1242/dev.128.6.1015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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