Article
Notch signaling directly controls cell proliferation in the Drosophila wing disc.
Proceedings of the National Academy of Sciences of the United States of America - 14 Mar 2000
Baonza A, Garcia-Bellido A
Abstract excerpt
Notch signaling is involved in cell differentiation and patterning during morphogenesis. In the Drosophila wing, Notch activity regulates the expression of several genes at the dorsal/ventral boundary, and this is thought to elicit wing-cell proliferation. In this work, we show the effect of clones of cells expressing different forms of several members of the Notch signaling pathway, which result in an alteration...
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