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Article

Identifications of three novel alleles of Serrate in Drosophila.

Cells & development - 1 Mar 2024

Zhang Qinghai, Zhang Pei, Yang Min, Tian Yingxue, Feng Chunxia, Wei Wei

Abstract excerpt

The Notch signaling pathway, an evolutionarily highly conserved pathway, participates in various essential physiological processes in organisms. Activation of Notch signaling in the canonical manner requires the combination of ligand and receptor. There are two ligands of Notch in Drosophila: Delta (Dl) and Serrate (Ser). A mutation mf157 is identified for causing nicks of fly wings in genetic analysis from a...

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Identifiers

PMID: 38403117
DOI: 10.1016/j.cdev.2024.203908

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Identifications of three novel alleles of Serrate in Drosophila.PMID 38403117Read ↗

The Drosophila gene Serrate encodes an EGF-like transmembrane protein with a complex expression pattern in embryos and wing discs.Semantic proximity Read ↗

Genetic and molecular characterization of a Notch mutation in its Delta- and Serrate-binding domain in Drosophila.Semantic proximity Read ↗

The Ser(+r83k) mutation is a second site mutation of SerD affecting the N-terminus of serrate.Semantic proximity Read ↗

Phenotypic and molecular characterization of SerD, a dominant allele of the Drosophila gene Serrate.Semantic proximity Read ↗

Secreted forms of DELTA and SERRATE define antagonists of Notch signaling in Drosophila.Semantic proximity Read ↗

The gene Serrate encodes a putative EGF-like transmembrane protein essential for proper ectodermal development in Drosophila melanogaster.Semantic proximity Read ↗

The Serrate locus of Drosophila and its role in morphogenesis of the wing imaginal discs: control of cell proliferation.Semantic proximity Read ↗

Beaded of Goldschmidt, an antimorphic allele of Serrate, encodes a protein lacking transmembrane and intracellular domains.Semantic proximity Read ↗

A mutation in EGF repeat-8 of Notch discriminates between Serrate/Jagged and Delta family ligands.Semantic proximity Read ↗

A dominant-negative form of Serrate acts as a general antagonist of Notch activation.Semantic proximity Read ↗

Modifications of the notch function by Abruptex mutations in Drosophila melanogaster.Semantic proximity Read ↗

Serrate2 is disrupted in the mouse limb-development mutant syndactylism.Semantic proximity Read ↗

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