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Article

HTLV-I and HTLV-II Tax: differences in induction of micronuclei in cells and transcriptional activation of viral LTRs.

Virology - 1 Mar 1996

Semmes O J, Majone F, Cantemir C, Turchetto L, Hjelle B, Jeang K T

Abstract excerpt

Human T-cell leukemia virus (HTLV) types I and II are highly related viruses that differ in disease manifestations. HTLV-I has been linked unmistakably to adult T-cell leukemia-lymphoma. On the other hand, there is little evidence that prior infection with HTLV-II increases risk for lymphoproliferative disorders. Both viruses encode homologous transcriptional-activating proteins (respectively designated as Tax1...

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Identifiers

PMID: 8599225
DOI: 10.1006/viro.1996.0126

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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HTLV-I and HTLV-II Tax: differences in induction of micronuclei in cells and transcriptional activation of viral LTRs.PMID 8599225Read ↗

Intracellular Localization and Cellular Factors Interaction of HTLV-1 and HTLV-2 Tax Proteins: Similarities and Functional DifferencesSemantic proximity Read ↗

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HTLV-1 Tax oncoprotein subverts the cellular DNA damage response via binding to DNA-dependent protein kinase.Semantic proximity Read ↗

A novel positive feedback-loop between the HTLV-1 oncoprotein Tax and NF-κB activity in T-cells.Semantic proximity Read ↗

Human T-cell leukemia virus type 2 tax mutants that selectively abrogate NFkappaB or CREB/ATF activation fail to transform primary human T cells.Semantic proximity Read ↗

Molecular mechanism of cell cycle progression induced by the oncogene product Tax of human T-cell leukemia virus type I.Semantic proximity Read ↗

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Transactivation of the human T-cell lymphotropic virus type 1 Tax1-responsive 21-base-pair repeats requires Holo-TFIID and TFIIA.Semantic proximity Read ↗

Suppression of DNA repair by HTLV type 1 Tax correlates with Tax trans-activation of proliferating cell nuclear antigen gene expression.Semantic proximity Read ↗

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