Article
Transcriptional effects on double-strand break-induced gene conversion tracts.
Mutation research - 16 Oct 2000
Weng Y S, Xing D, Clikeman J A, Nickoloff J A
Abstract excerpt
Transcription stimulates spontaneous homologous recombination, but prior studies have not investigated the effects of transcription on double-strand break (DSB)-induced recombination in yeast. We examined products of five ura3 direct repeat substrates in yeast using alleles that were transcribed at low or high levels. In each strain, recombination was stimulated by DSBs created in vivo at an HO site in one copy...
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