Article
Gene-conversion tract directionality is influenced by the chromosome environment.
Current genetics - 1 Oct 1998
Cho J W, Khalsa G J, Nickoloff J A
Abstract excerpt
Spontaneous and double-strand break (DSB)-induced gene conversion in Saccharomyces cerevisiae was assayed using non-tandem chromosomal direct repeat crosses and plasmid x chromosome crosses. Each cross involved identical ura3 alleles marked with phenotypically silent restriction fragment length polymorphic (RFLP) mutations at approximately 100-bp intervals. DSBs introduced in vivo at HO sites in one allele...
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