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Article

Early induction of alterations in cancellous and cortical bone histology after orchiectomy in mature rats.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Nov 1995

Gunness M, Orwoll E

Abstract excerpt

Androgen deficiency is associated with low bone mass in humans and animals, but the remodeling alterations that lead to bone loss are unclear. Our objective was to define early responses in both cancellous and cortical bone to orchiectomy (ORX) using histomorphometry in sexually mature (4-month-old) rats. A total of 62 male rats, 4 months of age, were divided into six groups, sham operated (SH) or orchiectomized...

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Identifiers

PMID: 8592951
DOI: 10.1002/jbmr.5650101117

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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