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Article

The Effects of Androgens on Murine Cortical Bone Do Not Require AR or ERα Signaling in Osteoblasts and Osteoclasts.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jul 2015

Ucer Serra, Iyer Srividhya, Bartell Shoshana M, Martin-Millan Marta, Han Li, Kim Ha-Neui, Weinstein Robert S, Jilka Robert L, O'Brien Charles A, Almeida Maria, Manolagas Stavros C

Abstract excerpt

In men, androgens are critical for the acquisition and maintenance of bone mass in both the cortical and cancellous bone compartment. Male mice with targeted deletion of the androgen receptor (AR) in mature osteoblasts or osteocytes have lower cancellous bone mass, but no cortical bone phenotype. We have investigated the possibility that the effects of androgens on the cortical compartment result from AR...

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Identifiers

PMID: 25704845
DOI: 10.1002/jbmr.2485
PMCID: PMC4871247

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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