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Article

Differential Effects of Neurectomy and Botox-induced Muscle Paralysis on Bone Phenotype and Titanium Implant Osseointegration.

Bone - 1 Dec 2021

Deng Jingyao, Cohen David J, Redden James, McClure Michael J, Boyan Barbara D, Schwartz Zvi

Abstract excerpt

Metabolic bone is highly innervated by both sensory and sympathetic nerves. In addition to skeletal development, neural regulation participates in local bone remodeling, which is important for successful osseointegration of titanium implants. Neurectomy is a model used to investigate the lack of neural function on bone homeostasis, but the relative impacts of direct denervation to bone or denervation-induced...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34390886
DOI: 10.1016/j.bone.2021.116145
PMCID: PMC8480339

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