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Article

Role of the androgen receptor in skeletal homeostasis: the androgen-resistant testicular feminized male mouse model.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Sept 2004

Vandenput Liesbeth, Swinnen Johannes V, Boonen Steven, Van Herck Erik, Erben Reinhold G, Bouillon Roger, Vanderschueren Dirk

Abstract excerpt

UNLABELLED: The role of androgen receptor-mediated androgen action on bone was investigated in testicular feminized male (Tfm) mice. Cortical bone was found to be unresponsive to testosterone (T) in orchidectomized Tfm mice, whereas cortical thickness as well as trabecular BMD and structure were fully maintained by T in the corresponding Tabby control mice. These data show an essential role for androgen...

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Source

Identifiers

PMID: 15312246
DOI: 10.1359/JBMR.040505

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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