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Article

Non-Nuclear–Initiated Actions of the Estrogen Receptor Protect Cortical Bone Mass

27 Feb 2013

Abstract excerpt

Extensive evidence has suggested that at least some of the effects of estrogens on bone are mediated via extranuclear estrogen receptor α signaling. However, definitive proof for this contention and the extent to which such effects may contribute to the overall protective effects of estrogens on bone maintenance have remained elusive. Here, we investigated the ability of a 17β-estradiol (E2) dendrimer conjugate...

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PMID: 23443267
DOI: 10.1210/me.2012-1368

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