Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prospective assessment of allelic losses at 4p14-16 in colorectal cancer: two mutational patterns and a locus associated with poorer survival.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Nov 1999

Arribas R, Ribas M, Risques R A, Masramon L, Tórtola S, Marcuello E, Aiza G, Miró R, Capellà G, Peinado M A

Abstract excerpt

Previous studies have shown that allelic losses in a locus mapping to the chromosomal region 4p14-16 are indicative of poor prognosis in colorectal cancer. To further characterize the region involved and to confirm earlier observations, we have analyzed losses of heterozygosity (LOH) in nine microsatellite markers spanning this region in a prospective series of 181 colorectal carcinomas. The extent and the nature...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 4
Share to Disease-Free Survival

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, p53

Share to Genes, ras

Share to Loss of Heterozygosity

Share to Lymphatic Metastasis

Share to Recurrence

Share to Survival Rate

Source

Identifiers

PMID: 10589758

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prospective assessment of allelic losses at 4p14-16 in colorectal cancer: two mutational patterns and a locus associated with poorer survival.PMID 10589758Read ↗

Chromosome 17p allelic loss in colorectal carcinoma. Clinical significance.Semantic proximity Read ↗

Correlation of allelic losses and clinicopathological factors in 504 primary breast cancers.Semantic proximity Read ↗

Allelic loss of chromosome 2p21-16.3 is associated with reduced survival in sporadic colorectal cancer.Semantic proximity Read ↗

Frequent genomic loss at chr16p13.2 is associated with poor prognosis in colorectal cancer.Semantic proximity Read ↗

Genetic classification of colorectal cancer based on chromosomal loss and microsatellite instability predicts survival.Semantic proximity Read ↗

At least two different regions are involved in allelic imbalance on chromosome arm 16q in breast cancer.Semantic proximity Read ↗

Three independently deleted regions at chromosome arm 16q in human prostate cancer: allelic loss at 16q24.1-q24.2 is associated with aggressive behaviour of the disease, recurrent growth, poor differentiation of the tumour and poor prognosis for the patient.Semantic proximity Read ↗

Allelic imbalance study of 16q in human primary breast carcinomas using microsatellite markers.Semantic proximity Read ↗

Allelic loss on chromosome 18q as a prognostic marker in stage II colorectal cancer.Semantic proximity Read ↗

Association of cumulative allelic losses with tumor aggressiveness in hepatocellular carcinoma.Semantic proximity Read ↗

A genome-wide map showing common regions of loss of heterozygosity/allelic imbalance in breast cancer.Semantic proximity Read ↗

Allelic loss on chromosome 17 in human ovarian cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.