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Article

Chromosomal region 15q21.1 is a frequent target of allelic imbalance in advanced breast carcinomas.

International journal of cancer - 10 Aug 2003

Rhiem Kerstin, Klein Annette, Münch Miriam, Kreutzfeld Rene, Ramser Juliane, Wardelmann Eva, Schackert Gabriele, Von Deimling Andreas, Wiestler Otmar D, Schmutzler Rita K

Abstract excerpt

Allelic imbalance constitutes a major mechanism of genetic aberrations in breast cancer and strongly indicates the involvement of tumor associated genes in the affected chromosomal regions. Preliminary results from our study indicated the existence of a tumor suppressor gene located on chromosomal arm 15q which may be involved in breast cancer progression.1 In the present study, 210 primary breast carcinomas, 30...

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PMID: 12794759
DOI: 10.1002/ijc.11169

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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