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Article

Kinetic analysis of the interaction between protein A domain variants and human Fc using plasmon resonance detection.

Journal of molecular recognition : JMR - 1 Jan 2000

Jendeberg L, Persson B, Andersson R, Karlsson R, Uhlén M, Nilsson B

Abstract excerpt

A real-time biospecific interaction analysis (BIA) was performed to study the specific interaction between the Fc portion of human immunoglobulin G1 (Fc1) and a one domain analogue (designated Z) of staphylococcal protein A, in monovalent (Z) and divalent (ZZ) forms, and five different single amino acid substituted Z variants (L17D, N28A, F30A, I31A, K35A). Experimental BIA data were used to calculate association...

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PMID: 8588944
DOI: 10.1002/jmr.300080405

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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