Article
Kinetic analysis of the interaction between protein A domain variants and human Fc using plasmon resonance detection.
Journal of molecular recognition : JMR - 1 Jan 2000
Jendeberg L, Persson B, Andersson R, Karlsson R, Uhlén M, Nilsson B
Abstract excerpt
A real-time biospecific interaction analysis (BIA) was performed to study the specific interaction between the Fc portion of human immunoglobulin G1 (Fc1) and a one domain analogue (designated Z) of staphylococcal protein A, in monovalent (Z) and divalent (ZZ) forms, and five different single ami...
Topics
- Amino Acid Sequence
- Biosensing Techniques
- CD4 Antigens
- Humans
- Immunoglobulin Fc Fragments
- Kinetics
- Models, Biological
- Molecular Sequence Data
- Mutation
- Protein Binding
- Protein Engineering
- Recombinant Proteins
- Reproducibility of Results
- Staphylococcal Protein A